On the genesis of spike-wave activity in a mean-field model of human brain activity

In this letter, the genesis of spike-wave activity - a hallmark of many generalized epileptic seizures - is investigated in a reduced mean-field model of human neural activity. Drawing upon brain modeling and dynamical systems theory, we demonstrate that the thalamic circuitry of the system is cruci...

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Bibliographic Details
Main Authors: Serafim Rodrigues, John R. Terry, Michael Breakspear
Format: Default Preprint
Published: 2005
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Online Access:https://hdl.handle.net/2134/475
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