Organocatalytic asymmetric domino Michael-Henry reaction for the synthesis of substituted bicyclo[3.2.1]octan-2-ones
The first organocatalytic asymmetric reaction between 1,4-cyclohexanedione and nitroalkenes have been studied, affording bicyclo[3.2.1]octane derivatives containing four continuous stereogenic centres. The products were obtained through a domino Michael-Henry process as a single diastereoisomer with...
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| Main Authors: | , , |
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| Format: | Default Article |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/2134/18334 |
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