Organocatalytic asymmetric domino Michael-Henry reaction for the synthesis of substituted bicyclo[3.2.1]octan-2-ones

The first organocatalytic asymmetric reaction between 1,4-cyclohexanedione and nitroalkenes have been studied, affording bicyclo[3.2.1]octane derivatives containing four continuous stereogenic centres. The products were obtained through a domino Michael-Henry process as a single diastereoisomer with...

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Bibliographic Details
Main Authors: Michail Tsakos, Mark Elsegood, Christoforos G Kokotos
Format: Default Article
Published: 2013
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Online Access:https://hdl.handle.net/2134/18334
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