An Au(I)-catalysed allenamide cyclisation giving access to an α-vinyl-substituted tetrahydroisoquinoline building block

An Au(I)-catalysed intramolecular hydroarylation of an enantiopure allenamide has been achieved and has given access to a key α-vinyl- substititued tetrahydroisoquinoline. Additionally this has been accomplished in very high yield and high diastereoselectivity. © Georg Thieme Verlag Stuttgart · New...

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Bibliographic Details

Main Authors:	Sanjitpal Singh, Mark Elsegood, Marc Kimber
Format:	Default Article
Published:	2012
Subjects:	Organic chemistry not elsewhere classified Other chemical sciences not elsewhere classified Alkaloids Allenamide Tetrahydroisoquinoline Au(I) catalysis Diastereoselective Chemical Sciences not elsewhere classified Organic Chemistry
Online Access:	https://hdl.handle.net/2134/13935
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