Development of a UHPLC-MS/MS (SRM) method for the quantitation of endogenous glucagon and dosed GLP-1 from human plasma

© 2017 Future Science Ltd. Aim: The performance of glucagon and GLP-1 immunoassays is often poor, but few sensitive LC-MS/MS methods exist as alternatives. Experimental: A multiplexed LC-MS/MS method using a 2D extraction technique was developed. Results: The method was established for the quantitat...

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Bibliographic Details

Main Authors:	James W. Howard, Richard G. Kay, Ben Jones, Jaimini Cegla, Tricia Tan, Steve Bloom, Colin Creaser
Format:	Default Article
Published:	2017
Subjects:	Other chemical sciences not elsewhere classified Glucagon GLP-1 Endogenous Plasma LC-MS/MS Immunoassay Cross-27 validation Supercharging mobile phase additive m-NBA Chemical Sciences not elsewhere classified
Online Access:	https://hdl.handle.net/2134/26217
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