A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(III)-based anion receptor

© 2019 The Royal Society of Chemistry. Enzymes that consume and produce nucleoside polyphosphate (NPP) anions represent major targets in drug discovery. For example, protein kinases are one of the largest classes of drug targets in the fight against cancer. The accurate determination of enzyme kinet...

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Bibliographic Details
Main Authors: Sarah Hewitt, Rozee Ali, Romain Mailhot, Chloe R. Antonen, Charlotte A. Dodson, Stephen Butler
Format: Default Article
Published: 2019
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Online Access:https://hdl.handle.net/2134/37952
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