Design, synthesis and antitrypanosomal activities of 2,6-disubstituted-4,5,7-Trifluorobenzothiophenes

Current treatments for Human African Trypanosomiasis (HAT) are limited in their application, have undesirable dosing regimens and unsatisfactory toxicities highlighting the need for the development of a safer drug pipeline. Our medicinal chemistry programme in developing rapidly accessible and modif...

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Bibliographic Details

Main Authors:	Avninder S. Bhambra, Mark Edgar, Mark Elsegood, Yuqi Li, George Weaver, Randolph R.J. Arroo, Vanessa Yardley, Hollie Burrell-Saward, Vladimir Krystof
Format:	Default Article
Published:	2016
Subjects:	Organic chemistry not elsewhere classified Other chemical sciences not elsewhere classified Benzothiophenes Fluorinated drugs Antitrypanosomal activity Sleeping sickness Human African Trypanosomiasis Trypanosoma brucei rhodesiense Chemical Sciences not elsewhere classified Organic Chemistry
Online Access:	https://hdl.handle.net/2134/19829
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