A rapid and highly diastereoselective synthesis of enantiomerically pure (4R,5R)- and (4S,5S)-isocytoxazone

A three-step protocol for the highly diastereoselective (>98%) synthesis of both (4R,5R)- and (4S,5S)-isocytoxazone from d- or l-tyrosine is reported. The diastereoselection was confirmed by X-ray crystallography. This synthesis is currently the highest yielding approach towards these enantiomeri...

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Bibliographic Details

Main Authors:	Benjamin Buckley, Philip C. Bulman Page, Vickie McKee
Format:	Default Article
Published:	2011
Subjects:	Organic chemistry not elsewhere classified Other chemical sciences not elsewhere classified Diastereoselective Cytoxazone Tyrosine Oxazolidinone Oxidation Chemical Sciences not elsewhere classified Organic Chemistry
Online Access:	https://hdl.handle.net/2134/13582
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