The use of shift reagents in ion mobility-mass spectrometry: studies on the complexation of an active pharmaceutical ingredient with polyethylene glycol excipients

Gas-phase ion mobility studies of mixtures containing polyethylene glycols (PEG) and an active pharmaceutical ingredient (API), Lamivudine, have been carried out using electrospray ionization-ion mobility spectrometry-quadrupole-time-of-flight mass spectrometry (ESI-IMS-Q-TOF). In addition to proton...

Full description

Saved in:
Bibliographic Details
Main Authors: Mark D. Howdle, Christine Eckers, Alice M.-F. Laures, Colin Creaser
Format: Default Article
Published: 2009
Subjects:
Other chemical sciences not elsewhere classified
Ion mobility spectrometry
Polyethylene glycol
Active pharmaceutical ingredient
Shift reagent
Quadrupole-time-of-flight mass spectrometry
Electrospray ionisation
Chemical Sciences not elsewhere classified
Online Access:https://hdl.handle.net/2134/4387
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items