Rapid assessment of site specific DNA methylation through resistive pulse sensing

Many diseases are defined by patterns of DNA methylation which result in aberrant gene expression. We present a rapid assay based upon resistive pulse sensing, RPS, to characterize sequence specific DNA methylation sites in genomic DNA. We modify the surface of superparamagnetic beads, SPBs, with DN...

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Bibliographic Details
Main Authors: Matthew Healey, William Rowe, Sofia Siati, Muttuswamy Sivakumaran, Mark Platt
Format: Default Article
Published: 2018
Subjects:
Other chemical sciences not elsewhere classified
Bioassay
Epigenetics
Methylation
Nanopore
Resistive pulse sensor
Chemical Sciences not elsewhere classified
Online Access:https://hdl.handle.net/2134/32424
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