Rapid determination of N-Methylpyrrolidine in Cefepime by combining direct infusion electrospray ionisation-time-of-flight mass spectrometry with field asymmetric waveform ion mobility spectrometry

The determination of N-methyl pyrrolidine, a potential impurity in the cephalosporin antibiotic cefepime, by direct infusion ESI combined with field asymmetric waveform ion mobility spectrometry-mass spectrometry (ESI-FAIMS-MS) is demonstrated. The addition of a chip-based FAIMS separation prior to...

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Bibliographic Details

Main Authors:	Robert W. Smith, Lisa B. Cox, Aswandi Yudin, Jim Reynolds, Mark Powell, Colin Creaser
Format:	Default Article
Published:	2015
Subjects:	Other chemical sciences not elsewhere classified Drug impurity FAIMS Electrospray mass spectrometry N-methyl pyrrolidine Cefepime Chemical Sciences not elsewhere classified
Online Access:	https://hdl.handle.net/2134/20586
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