Total synthesis of the tetrasubstituted furan fatty acid metabolite CeDFP via Au-catalyzed intermolecular alkyne hydroarylation

The first total synthesis of the tetrasubstituted furan fatty acid (FFA) metabolite 5-[(1 E)-2-carboxyethenyl]-3,4-dimethyl-2-furanpentanoic acid (CeDFP) is reported. CeDFP is a FFA metabolite isolated from shark livers and is related to the known FFA metabolites CMPF and CMPentylF. Key elements of...

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Bibliographic Details
Main Authors: Yamin Wang, Gareth Pritchard, Marc Kimber
Format: Default Article
Published: 2019
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Online Access:https://hdl.handle.net/2134/38181
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