Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery

Tyrosine sulfation is a post-translational modification that enhances protein–protein interactions and may identify druggable sites in the extracellular space. The G protein-coupled receptor CXCR4 is a prototypical example with three potential sulfation sites at positions 7, 12, and 21. Each recepto...

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Bibliographic Details
Main Authors: Joshua J. Ziarek, Anthony E. Getschman, Stephen Butler, Deni Taleski, Bryan Stephens, Irina Kufareva, Tracy M. Handel, Richard J. Payne, Brian F. Volkman
Format: Default Article
Published: 2013
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Online Access:https://hdl.handle.net/2134/18769
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