Palladium-catalyzed stereoselective intramolecular oxidative amidation of alkenes in the synthesis of 1,3- and 1,4-amino alcohols and 1,3-diamines

An efficient and practical Pd-catalyzed intramolecular oxidative allylic amidation provides facile access to derivatives of 1,3- and 1,4-amino alcohols and 1,3-diamines. The method operates under mild reaction conditions (RT) with molecular oxygen (1 atm) as the sole reoxidant of Pd. Excellent diast...

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Bibliographic Details
Main Authors: Andrei Malkov, Darren S. Lee, Mark Elsegood, Maciej Barlog, Pavel Kocovsky
Format: Default Article
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/2134/15475
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