A novel bifunctional allyldisilane as a triple allylation reagent in the stereoselective synthesis of trisubstituted tetrahydrofurans

Three for the price of two: A bifunctional allyldisilane undergoes a two-step triple allylation sequence with pairs of aldehydes to give all-cis trisubstituted tetrahydrofurans in excellent enantio- and diastereoselectivity (see scheme). The first allylation step, which sets up the key stereogenic c...

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Bibliographic Details
Main Authors: Andrei Malkov, Ondrej Kysilka, Mark Edgar, Aneta Kadlcikova, Martin Kotora, Pavel Kocovsky
Format: Default Article
Published: 2011
Subjects:
Other chemical sciences not elsewhere classified
Allylation
Asymmetric catalysis
Rearrangement
Silanes
Stereoselectivity
Chemical Sciences not elsewhere classified
Online Access:https://hdl.handle.net/2134/13545
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