Isoindolinones as versatile new chiral templates for use in asymmetric synthesis
Reaction of β-aminothiols with 2-acylbenzoic acids affords the thiazoloisoindolinones (1) as single diastereoisomers when using chiral non-racemic aminothiol substrates. Attempted diastereoselective enolate alkylation of (1) led to the formation of the S-alkylated products (2). Treatment of the sulp...
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| Format: | Default Thesis |
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2003
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| Online Access: | https://hdl.handle.net/2134/36122 |
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