Mass spectrometric studies of the biological fate of platinum-based drugs and selenium supplementation in cancer chemotherapy

Platinum-based drugs are an important group of alkylating-like agents which are used in cancer chemotherapy treatment. Cisplatin and oxaliplatin in particular are still commonly used today and are the focus of this thesis. As with most chemotherapy drugs, the efficacy of these drugs are limited by t...

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Bibliographic Details
Main Author: Sarah E. Taylor
Format: Default Thesis
Published: 2014
Subjects:
Other chemical sciences not elsewhere classified
Pt-based drugs
Oxaliplatin
Cisplatin
Pt-DNA Adducts
Platinum
Selenium
MSA
Clinical samples
Cell culture
ICP-MS
ESI-MS
Chemical Sciences not elsewhere classified
Online Access:https://hdl.handle.net/2134/17448
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https://hdl.handle.net/2134/17448

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