Synthesis of potentially cytotoxic steroidal lactones
A review of the biological properties and the synthesis of α-methylene-γ- and -δ-lactones is presented. Cholesterol (201) was converted into 4-oxa-3-oxo-5α-cholestane (203) and the α-methylene moiety was introduced by α-hydroxymethylenation, diethylamination and elimination of diethylamine after hyd...
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| Format: | Default Thesis |
| Published: |
1979
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| Online Access: | https://hdl.handle.net/2134/36166 |
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