Stereochemical aspects in the aminoalkylation reactions of ketones

A simple "one-pot" method has been developed for the amino-methylation of ketones possessing an α-hydrogen under aprotic conditions. The procedure utilises chlorotrimethylsilane in the sequential formation of the intermediate trimethylsilyl enol ether and methylene iminium species. The met...

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Bibliographic Details
Main Author: Robin A. Fairhurst
Format: Default Thesis
Published: 1991
Subjects:
Online Access:https://hdl.handle.net/2134/28437
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