The role of DNA methylation in aging, rejuvenation, and age-related disease

DNA methylation is a major control program that modulates gene expression in a plethora of organisms. Gene silencing through methylation occurs through the activity of DNA methyltransferases, enzymes that transfer a methyl group from S-adenosyl-l-methionine to the carbon 5 position of cytosine. DNA...

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Bibliographic Details
Main Authors: Adiv A. Johnson, Kemal Akman, Stuart R.G. Calimport, Daniel Wuttke, Alexandra Stolzing, Joao Pedro De Magalhaes
Format: Default Article
Published: 2012
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Online Access:https://hdl.handle.net/2134/16821
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