Friction in ultra-thin conjunction of valve seals of pressurised metered dose inhalers

In many drug dispensing devices, such as syringes and inhalers, a rubber disk is used as a seal. During device actuation the seal is subjected to friction which in turn causes its deformation. This can lead to suboptimal performance of the device and consequent variability in delivered dose. Seal fr...

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Bibliographic Details
Main Authors: Polina Prokopovich, Stephanos Theodossiades, Homer Rahnejat, D. Hodson
Format: Default Article
Published: 2010
Subjects:
Mechanical engineering not elsewhere classified
PMDI valve
Elastomeric seals
Friction
Adhesion
Mechanical Engineering not elsewhere classified
Mechanical Engineering
Online Access:https://hdl.handle.net/2134/13330
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https://hdl.handle.net/2134/13330

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