Cellular senescence: immunosurveillance and future immunotherapy

In response to persistent DNA damage, induction into cell senescence promotes an immunogenic program which facilitates immune clearance of these damaged cells. Under physiological conditions, senescent cells can activate both innate and adaptive immune responses, functioning to maintain tissue homeo...

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Bibliographic Details
Main Authors: Dominick Burton, Alexandra Stolzing
Format: Default Article
Published: 2018
Subjects:
Mechanical engineering not elsewhere classified
Ageing
Immunosurviellance
Immunotherapy
Macrophages
Senescence
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/31884
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https://hdl.handle.net/2134/31884

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