The aging signature: a hallmark of induced pluripotent stem cells?

The discovery that somatic cells can be induced into a pluripotent state by the expression of reprogramming factors has enormous potential for therapeutics and human disease modeling. With regard to aging and rejuvenation, the reprogramming process resets an aged, somatic cell to a more youthful sta...

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Bibliographic Details
Main Authors: Leili Rohani, Adiv A. Johnson, Antje Arnold, Alexandra Stolzing
Format: Default Article
Published: 2014
Subjects:
Mechanical engineering not elsewhere classified
Aging
Differentiation
Epigenetic
Induced pluripotent stem
Reprogramming
Telomeres
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/16814
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