A mathematical model demonstrating the role of interstitial fluid flow on the clearance and accumulation of amyloid β in the brain

A system of partial differential equations is developed to describe the formation and clearance of amyloid β (Aβ) and the subsequent buildup of Aβ plaques in the brain, which are associated with Alzheimer’s disease. The Aβ related proteins are divided into five distinct categories depending on their...

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Bibliographic Details

Main Authors:	C.Y. Chen, Y.H. Tseng, John Ward
Format:	Default Article
Published:	2019
Subjects:	Bioinformatics Mathematical Sciences Biological Sciences Mathematical model Alzheimer’s disease Amyloid β Brain Interstitial fluid Advection Plaque formation
Online Access:	https://hdl.handle.net/2134/9810737.v1
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