Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process

A scalable low-shear membrane emulsification process was used to produce microencapsulated Escherichia coli-phages in a solid oral dosage form. Uniform pH-responsive composite microparticles (mean size ~100 µm) composed of Eudragit® S100 and alginate were produced. The internal microstructure of the...

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Bibliographic Details
Main Authors: Gurinder K. Vinner, Kerry Richards, Miika Leppanen, Antonia P. Sagona, Danish Malik
Format: Default Article
Published: 2019
Subjects:
Pharmacology and Pharmaceutical Sciences
Microencapsulation,
Bacteriophage therapy
Controlled release
Enteric infections
pH-triggered release
E. coli
Eudragit S100
Online Access:https://hdl.handle.net/2134/9849674.v1
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