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iPiG: integrating peptide spectrum matches into genome browser visualizations

Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass s...

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Bibliographic Details
Published in:PloS one 2012-12, Vol.7 (12), p.e50246-e50246
Main Authors: Kuhring, Mathias, Renard, Bernhard Y
Format: Article
Language:English
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Summary:Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from https://sourceforge.net/projects/ipig/. It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0050246