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iPiG: integrating peptide spectrum matches into genome browser visualizations
Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass s...
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Published in: | PloS one 2012-12, Vol.7 (12), p.e50246-e50246 |
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description | Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from https://sourceforge.net/projects/ipig/. It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online. |
doi_str_mv | 10.1371/journal.pone.0050246 |
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subjects | Algorithms Analysis Annotations Bioinformatics Biology Computer Graphics Computer Science Databases, Protein Genes Genomes Genomics Identification Java (Programming language) Mass spectrometry Mass spectroscopy Open source software Peptides Peptides - chemistry Peptides - genetics Proteins Proteomics Scientific imaging Spectroscopy User-Computer Interface Visualization (Computer) Web browsers Zebrafish |
title | iPiG: integrating peptide spectrum matches into genome browser visualizations |
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